This is because some conditions affect the amounts of albumin or globulin in the blood.Ī low A/G ratio may be due to an overproduction of globulin, underproduction of albumin, or loss of albumin, which may indicate the following: kidney disease, such as nephrotic syndrome or glomerulonephritisĪlongside the serum total protein level, a laboratory may calculate the albumin to globulin (A/G) ratio in the bloodstream.malabsorption disorders, such as celiac disease or inflammatory bowel disease (IBD).Low serum total protein levels may suggest any of the following health conditions: inflammation from infections, such as HIV or viral hepatitis.What do high protein levels mean?Ĭonsistently high serum total protein levels can indicate the following health conditions: If protein levels are not healthy, the doctor may recommend further tests. They will analyze the results in the context of a person’s overall CMP. However, problems with the urinary tract, such as chronic kidney disease, can cause large amounts of protein to leak into the urine.Ī doctor will look at the results of the serum total protein test along with other test results to help diagnose medical conditions. The kidneys filter albumin and other proteins from the blood so that the urine may contain small amounts of protein. They include carrier proteins, enzymes, complement, and immunoglobulins (also called antibodies).Ī urine total protein test detects the amounts of protein present in the urine. They are grouped by how they migrate on electrophoresis and include α1, α2, β and γ fractions. Globulin proteins vary in size, weight, and function.
It regulates oncotic pressure in the plasma to prevent water from leaking out of the blood vessels. Albumin protein accounts for half of the total protein found in blood plasma.Blood testĪ serum total protein test measures the amount of albumin and globulin present in the serum portion of the blood: The test examines protein in either urine or the liquid portion of the blood, which medial professionals call the serum. Proteins are essential for overall health, which is why routine health checkups often include a total protein test.Ī total protein test measures the total number of proteins present in body fluid. Proteins serve as building blocks for many organs, hormones, and enzymes. Share on Pinterest The total protein test can help a doctor diagnose various conditions.
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